Description

3-Fluorotetrahydro-2H-Pyran-4-Amine is a valuable fluorinated heterocyclic amine building block, identified by CAS NO 1416371-97-5. This compound is essential for introducing both fluorine and amine functionalities into complex molecular architectures, enabling the fine-tuning of physicochemical and biological properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance bioavailability and environmental stability.
• Chemical Biology Probe: Serves as a versatile building block for creating molecular probes and tools to study biological processes and enzyme functions.
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials that require specific amine and fluorine components.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Fluorotetrahydro-2H-Pyran-4-Amine
CAS No.	1416371-97-5
Molecular Formula	C5H10FNO
Molecular Weight	119.14 g/mol
Synonyms	4-Amino-3-fluorotetrahydro-2H-pyran; 3-Fluoro-4-aminotetrahydropyran; 3-Fluoro-4-aminotetrahydro-2H-pyran; 3-Fluoro-4-aminotetrahydropyran; 4-Amino-3-fluorotetrahydropyran; 3-Fluoro-tetrahydro-pyran-4-ylamine; 3-Fluoro-4-aminotetrahydro-2H-pyran; 3-Fluoro-4-aminotetrahydropyran
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production of 3-Fluorotetrahydro-2H-Pyran-4-Amine adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability for your critical synthesis workflows. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.