Description

[3-(Oxetan-3-Yloxy)Phenyl]Methanamine is a specialized aromatic amine derivative featuring an oxetane ether linkage, offering a unique structural motif for advanced chemical synthesis. This compound is valued for its role as a key building block in pharmaceutical research and development, particularly in the design of novel small molecule therapeutics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Proteolysis Targeting Chimera (PROTAC) Linker Chemistry: Utilized in the construction of heterobifunctional molecules due to its amine functionality and stable oxetane spacer.
• Agrochemical Synthesis: Serves as a precursor in the development of new generation herbicides and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Chemical Biology Probe Synthesis: Incorporated into molecular probes for studying enzyme function and protein-protein interactions.

Basic Information

Product Name	[3-(Oxetan-3-Yloxy)Phenyl]Methanamine
CAS No.	1416323-28-8
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(3-(Oxetan-3-yloxy)phenyl)methanamine; 1-[3-(Oxetan-3-yloxy)phenyl]methanamine; 3-(Oxetan-3-yloxy)benzylamine; (3-(Oxetane-3-yloxy)phenyl)methylamine; Benzenemethanamine, 3-(3-oxetanyloxy)-; CAS 1416323-28-8; Oxetane-3-yloxy benzylamine derivative
EINECS	Contact for details

Quality Control

Every batch of [3-(Oxetan-3-Yloxy)Phenyl]Methanamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.