Description

n-[(1S,2S)-1,2-Diphenyl-2-(1-Piperidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is a sophisticated chiral thiourea derivative designed for advanced chemical synthesis and research. This compound is significant for its role as a key intermediate or building block in the development of pharmaceuticals and bioactive molecules, particularly those targeting glycosidase enzymes or requiring specific stereochemical control. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those with glycosidase inhibitory activity or chiral amine pharmacophores.
• Biochemical Research: Used as a tool compound or probe in enzymatic studies, particularly for investigating carbohydrate-processing enzymes and their inhibitors.
• Asymmetric Catalyst/Organocatalyst Precursor: The thiourea moiety can be utilized in the development of chiral catalysts for enantioselective synthesis.
• Glycoconjugate Synthesis: Acts as a protected glycosyl donor or acceptor intermediate in the preparation of complex carbohydrate-based molecules.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development and quality control in API manufacturing.
• Custom Synthesis & Contract Manufacturing: A starting point for the custom synthesis of specialized compounds for client-specific R&D projects.

Basic Information

Product Name	n-[(1S,2S)-1,2-Diphenyl-2-(1-Piperidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea
CAS No.	1416133-16-8
Molecular Formula	C36H43N3O9S
Molecular Weight	693.81 g/mol
Synonyms	1-[(1S,2S)-1,2-Diphenyl-2-(piperidin-1-yl)ethyl]-3-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)]thiourea; (1S,2S)-N-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosylcarbamothioyl)-1,2-diphenyl-2-(piperidin-1-yl)ethan-1-amine; Acetylated Glucosyl Thiourea Derivative; Chiral Diphenylpiperidinyl Ethyl Thiourea-Glucose Conjugate
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-1,2-Diphenyl-2-(1-Piperidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity (HPLC), and specific rotation are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.