Description

n-[(1R,2R)-1,2-Diphenyl-2-(1-Pyrrolidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea CAS NO 1416133-15-7 is a sophisticated chiral thiourea derivative, a key intermediate in advanced organic synthesis. This compound is valued for its role in the development of glycosidase inhibitors and other biologically active molecules, offering a unique scaffold for pharmaceutical research. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, carbohydrate chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of potential glycosidase inhibitors and other bioactive compounds.
• Medicinal Chemistry Research: Used as a chiral scaffold in structure-activity relationship (SAR) studies and lead optimization.
• Carbohydrate Chemistry: Serves as a key reagent in the synthesis of complex, acetyl-protected glyco-conjugates and mimics.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme mechanisms and carbohydrate-protein interactions.
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.

Basic Information

Product Name	n-[(1R,2R)-1,2-Diphenyl-2-(1-Pyrrolidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea
CAS No.	1416133-15-7
Molecular Formula	C₃₅H₄₁N₃O₉S
Molecular Weight	679.78 g/mol
Synonyms	(1R,2R)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethyl (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)carbamothioate; N-[(1R,2R)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethyl]-N'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea; β-D-Glucopyranoside, 2,3,4,6-tetra-O-acetyl-, 1-[[[[(1R,2R)-1,2-diphenyl-2-(1-pyrrolidinyl)ethyl]amino]thioxomethyl]amino]-1-deoxy-; Thiourea, N-[(1R,2R)-1,2-diphenyl-2-(1-pyrrolidinyl)ethyl]-N'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and chiral integrity. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.