Description

n-[(1S,2S)-1,2-Diphenyl-2-(1-Pyrrolidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea CAS NO 1414889-06-7 is a sophisticated chiral thiourea derivative, a key synthetic intermediate in modern organic and medicinal chemistry. Its value lies in its precise stereochemistry and functional groups, which make it an essential building block for constructing complex molecules with high enantiomeric purity. This compound is primarily required by research institutions and pharmaceutical companies engaged in the development of glycosidase inhibitors, carbohydrate-based therapeutics, and novel chiral catalysts.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glycosidase inhibitors and carbohydrate-based drug candidates targeting metabolic and viral diseases.
• Chiral Catalyst/Organocatalyst Precursor: Serves as a precursor or ligand in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds.
• Glycobiology Research: Used in the study of carbohydrate-protein interactions, enzyme mechanisms, and the development of chemical probes.
• Chemical Biology Tool: Employed in the design and synthesis of activity-based probes (ABPs) or affinity labels for enzyme target identification.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel, targeted agrochemicals with specific modes of action.
• Academic & Process Chemistry: Utilized in methodological development and scale-up studies for complex organic transformations in academic and industrial R&D settings.

Basic Information

Product Name	n-[(1S,2S)-1,2-Diphenyl-2-(1-Pyrrolidinyl)Ethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea
CAS No.	1414889-06-7
Molecular Formula	C35H43N3O9S
Molecular Weight	681.80 g/mol
Synonyms	(1S,2S)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethyl (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)carbamimidothioate; 1-[(1S,2S)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethyl]-3-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)]thiourea; N-[(1S,2S)-1,2-Diphenyl-2-(1-pyrrolidinyl)ethyl]-N'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea; Acetylated Glucopyranosyl Thiourea Derivative; Chiral Thiourea-Glucose Conjugate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data, including HPLC purity, chiral purity, and structural confirmation via NMR and MS. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for identity, purity, and related substances. Our quality management system supports development under cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.