Description

n-[(1S,2S)-2-(Dimethylamino)-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)- Thiourea is a sophisticated chiral thiourea derivative, a key intermediate in advanced organic synthesis and pharmaceutical research. Its molecular architecture, featuring a glucopyranosyl moiety and a chiral diamine backbone, makes it a valuable ligand for asymmetric catalysis and a crucial building block for the development of glycosidase inhibitors and other bioactive molecules. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and specialized fine chemical production, where precise stereochemistry and functional group compatibility are paramount.

Application

• Asymmetric Catalysis: Serves as a chiral organocatalyst or ligand precursor for enantioselective synthesis reactions.
• Pharmaceutical Intermediate: A critical building block in the research and development of novel glycosidase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the creation of advanced, chiral active ingredients for crop protection products.
• Glycochemistry Research: A valuable tool for studying carbohydrate-protein interactions and designing glycomimetics.
• Chiral Auxiliary/Resolving Agent: Can be employed for the separation of enantiomers or to induce chirality in synthetic pathways.
• Academic & Industrial R&D: A high-value reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	n-[(1S,2S)-2-(Dimethylamino)-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)- Thiourea
CAS No.	1414889-04-5
Molecular Formula	C₃₃H₄₁N₃O₉S
Molecular Weight	631.76 g/mol
Synonyms	(1S,2S)-N1,N1-Dimethyl-1,2-diphenylethane-1,2-diamine N-[(2R,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(acetoxymethyl)oxan-2-yl]carbamimidothioic acid derivative; 1-((2S,3S)-3-(Dimethylamino)-2,3-diphenylpropyl)-3-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)thiourea tetraacetate; Chiral Glucosyl Thiourea Derivative; Acetylated Glucopyranosyl Thiourea Ligand; (S,S)-DPEN-derived glucosyl thiourea.
EINECS	Contact for details

Quality Control

Our production of n-[(1S,2S)-2-(Dimethylamino)-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)- Thiourea adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.