Description

Methyl 3,4-Dihydro-2H-Pyrano-[2,3-B]Pyridine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1414864-15-5. This compound is a critical building block in modern medicinal chemistry, valued for its fused pyranopyridine scaffold which is integral to developing novel bioactive molecules. It is primarily sought by research organizations and pharmaceutical manufacturers engaged in the synthesis of new chemical entities for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to introduce the dihydropyrano[2,3-b]pyridine moiety into target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Methyl 3,4-Dihydro-2H-Pyrano-[2,3-B]Pyridine-6-Carboxylate
CAS No.	1414864-15-5
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	Methyl 3,4-dihydro-2H-pyrano[2,3-b]pyridine-6-carboxylate; 6-Carbomethoxy-3,4-dihydro-2H-pyrano[2,3-b]pyridine; Methyl 3,4-dihydro-2H-pyrano[2,3-b]pyridine-6-carboxylate; 2H-Pyrano[2,3-b]pyridine-6-carboxylic acid, 3,4-dihydro-, methyl ester; 1414864-15-5; Pyrano[2,3-b]pyridine-6-carboxylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 3,4-Dihydro-2H-Pyrano-[2,3-B]Pyridine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.