Description

(3-Aminocyclobutyl)Acetic Acid is a versatile bifunctional organic building block featuring both a primary amine and a carboxylic acid group on a strained cyclobutane ring. This unique structure makes it a valuable intermediate for the synthesis of novel pharmacologically active compounds, particularly in medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical companies for developing new therapeutic agents, including protease inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, especially in protease inhibitor programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained cyclobutane scaffold.
• Peptidomimetic Synthesis: Serves as a conformationally restricted amino acid analog for designing bioactive peptides.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for target validation.
• Agrochemical Research: Potential intermediate for developing new active ingredients with novel modes of action.
• Material Science: Can be used as a monomer or cross-linker for specialty polymers.

Basic Information

Product Name	(3-Aminocyclobutyl)Acetic Acid
CAS No.	1408076-40-3
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	2-(3-Aminocyclobutyl)acetic acid; 3-Aminocyclobutaneacetic acid; (3-Aminocyclobutyl)ethanoic acid; 1-Amino-3-(carboxymethyl)cyclobutane; Cyclobutaneacetic acid, 3-amino-; 3-Aminocyclobutylacetic Acid; 1408076-40-3; (3-Aminocyclobutyl)Acetic Acid
EINECS	Contact for details

Quality Control

Our (3-Aminocyclobutyl)Acetic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for laboratory and pilot-scale materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.