Description

trans-3-Ethoxycyclobutan-1-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its unique cyclobutane scaffold and amine functionality, which are critical for constructing complex molecules in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural properties for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor for the introduction of the ethoxycyclobutylamine moiety into more complex organic frameworks.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal complexes.
• Academic & Industrial R&D: Essential for chemical biology studies and process chemistry optimization in both academic and industrial laboratory settings.

Basic Information

Product Name	trans-3-Ethoxycyclobutan-1-Amine Hydrochloride
CAS No.	1408076-27-6
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	trans-1-Amino-3-ethoxycyclobutane hydrochloride; (1r,3r)-3-Ethoxycyclobutan-1-amine hydrochloride; 3-Ethoxycyclobutan-1-amine hydrochloride (trans-); 1408076-27-6; trans-3-Ethoxycyclobutylamine HCl; (trans)-3-Ethoxycyclobutanamine hydrochloride; 1-Amino-3-ethoxycyclobutane HCl (trans-); Cyclobutanamine, 3-ethoxy-, hydrochloride, (1r,3r)-
EINECS	Contact for details

Quality Control

Our trans-3-Ethoxycyclobutan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.