Description

Ethyl 5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant building block and intermediate used in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in medicinal chemistry and drug discovery programs. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for API development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in the discovery and optimization of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetics Synthesis: Serves as a constrained amino acid analog for creating peptide-like molecules with enhanced stability and bioavailability.
• Agrochemical Development: Employed in the research and production of advanced pesticides and herbicides.
• Catalyst and Ligand Preparation: Used as a precursor for chiral catalysts and ligands in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services at various scales.

Basic Information

Product Name	Ethyl 5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride
CAS No.	1408074-45-2
Molecular Formula	C8H16ClNO3
Molecular Weight	209.67 g/mol
Synonyms	5-Amino-tetrahydro-2H-pyran-2-carboxylic acid ethyl ester hydrochloride; Ethyl 5-aminotetrahydropyran-2-carboxylate hydrochloride; 2H-Pyran-2-carboxylic acid, 5-amino-tetrahydro-, ethyl ester, hydrochloride; Ethyl 5-aminotetrahydro-2H-pyran-2-carboxylate HCl; 5-Amino-tetrahydropyran-2-carboxylic acid ethyl ester HCl; 1408074-45-2
EINECS	Contact for details

Quality Control

Our Ethyl 5-Amino-Tetrahydro-Pyran-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.