Description

4-Amino-4-Hydroxymethyl-Tetrahydro-2H-Pyran Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex molecules, offering a unique scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands.
• Academic & Institutional Research: Used in universities and research institutes for synthetic organic chemistry and methodological studies.

Basic Information

Product Name	4-Amino-4-Hydroxymethyl-Tetrahydro-2H-Pyran Hydrochloride
CAS No.	1404373-79-0
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	4-Amino-4-(hydroxymethyl)tetrahydro-2H-pyran hydrochloride; 4-(Aminomethyl)-4-hydroxytetrahydro-2H-pyran hydrochloride; Tetrahydro-2H-pyran-4-amine, 4-(hydroxymethyl)-, hydrochloride; 4-Aminomethyl-4-hydroxy-tetrahydropyran hydrochloride; 4-Hydroxymethyl-4-aminotetrahydropyran HCl; 4-Amino-4-hydroxymethyl-tetrahydropyran HCl; (4-Hydroxymethyl-tetrahydro-pyran-4-yl)-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-4-Hydroxymethyl-Tetrahydro-2H-Pyran Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.