Description

trans-2-Hydroxycyclobutane-1-Carboxylic Acid is a high-purity, functionalized cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and intermediate for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including protease inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	trans-2-Hydroxycyclobutane-1-Carboxylic Acid
CAS No.	1403894-01-8
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(1R,2S)-2-Hydroxycyclobutane-1-carboxylic Acid; (1S,2R)-2-Hydroxycyclobutane-1-carboxylic Acid; trans-2-Hydroxycyclobutanecarboxylic Acid; 2-Hydroxycyclobutane-1-carboxylic Acid, trans-; Cyclobutanecarboxylic acid, 2-hydroxy-, (1R,2S)-rel-; (1R,2S)-rel-2-Hydroxycyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our trans-2-Hydroxycyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting customer specifications and research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.