Description

5-Amino-Tetrahydro-2H-Pyran-3-Ol is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both amino and hydroxyl groups on a saturated pyran ring, makes it a versatile chiral intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its functional groups for targeted biological activity.
• Fine Chemical Production: Acts as a building block for specialty chemicals, including chiral ligands, catalysts, and advanced materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Peptidomimetics & Bioisosteres: The scaffold is valuable for designing peptide mimics and bioisosteric replacements in medicinal chemistry programs.

Basic Information

Product Name	5-Amino-Tetrahydro-2H-Pyran-3-Ol
CAS No.	1403864-10-7
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	5-Aminotetrahydro-2H-pyran-3-ol; 3-Pyranol, 5-amino-tetrahydro-; 5-Amino-3-hydroxytetrahydropyran; 3-Hydroxy-5-aminotetrahydropyran; Tetrahydro-2H-pyran-3-ol, 5-amino-; 5-Amino-3-hydroxypiperidine (tautomeric form); 5-Aminotetrahydro-2H-pyran-3-one (related oxo form); 1403864-10-7
EINECS	Contact for details

Quality Control

Our 5-Amino-Tetrahydro-2H-Pyran-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.