Description

Pyrido[3,4-C]Pyridazine-7(6H)-Carboxylic Acid, 3-Chloro-5,8-Dihydro-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block for kinase inhibitors. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, especially those targeting specific kinase pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential therapeutic effects.
• API Synthesis: Serves as a precursor in the production of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical development.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme inhibition and cellular signaling mechanisms.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in custom synthesis for pharmaceutical clients.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Item	Details
Product Name	Pyrido[3,4-C]Pyridazine-7(6H)-Carboxylic Acid, 3-Chloro-5,8-Dihydro-, 1,1-Dimethylethyl Ester
CAS No.	1402672-42-7
Molecular Formula	C14H16ClN3O2
Molecular Weight	293.75 g/mol
Synonyms	tert-Butyl 3-chloro-5,8-dihydropyrido[3,4-c]pyridazine-7(6H)-carboxylate; 3-Chloro-5,8-dihydro-6H-pyrido[3,4-c]pyridazine-7-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 3-chloro-5,8-dihydro-6H-pyrido[3,4-c]pyridazine-7-carboxylate; 3-Chloro-5,8-dihydropyrido[3,4-c]pyridazine-7(6H)-carboxylic acid tert-butyl ester; 1402672-42-7; tert-Butyl 3-chloro-5,6,7,8-tetrahydropyrido[3,4-c]pyridazine-7-carboxylate
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-C]Pyridazine-7(6H)-Carboxylic Acid, 3-Chloro-5,8-Dihydro-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.