Description

cis-4-Amino-Tetrahydro-Furan-3-Carboxylic Acid Methyl Ester is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small molecule therapeutics.
• Peptidomimetics Research: Used to incorporate constrained, furanoid amino acid motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for developing new chiral active ingredients with specific biological activity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Chemical Biology Probes: Utilized to create labeled or modified compounds for studying biological pathways and target engagement.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical space in medicinal chemistry programs.

Basic Information

Product Name	cis-4-Amino-Tetrahydro-Furan-3-Carboxylic Acid Methyl Ester
CAS No.	1402565-76-7
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	Methyl cis-4-aminotetrahydrofuran-3-carboxylate; (3R,4S)-4-Amino-3-methoxycarbonyltetrahydrofuran; (3S,4R)-4-Amino-3-methoxycarbonyltetrahydrofuran; 4-Amino-tetrahydro-furan-3-carboxylic acid methyl ester, cis-; 3-Furancarboxylic acid, 4-amino-tetrahydro-, methyl ester, cis-; 4-Aminotetrahydrofuran-3-carboxylic Acid Methyl Ester; Furan-3-carboxylic acid, 4-amino-tetrahydro-, methyl ester
EINECS	Contact for details

Quality Control

Our cis-4-Amino-Tetrahydro-Furan-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.