Description

2-Chloro-4-(Thiazol-5-Yl)Aniline is a high-value, multi-functional aromatic amine building block featuring a unique heterocyclic thiazole substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), enabling the development of novel molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aniline core.
• Material Science Research: Serves as a precursor for organic electronic materials, including charge-transport layers and light-emitting compounds.
• Ligand and Catalyst Development: The aniline and thiazole functionalities make it a useful starting point for designing novel chelating ligands and organocatalysts.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized heterocyclic dyes and colorants.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring this precise molecular scaffold.

Basic Information

Product Name	2-Chloro-4-(Thiazol-5-Yl)Aniline
CAS No.	1400287-28-6
Molecular Formula	C9H7ClN2S
Molecular Weight	210.68 g/mol
Synonyms	5-(2-Chloro-4-aminophenyl)thiazole; 4-Amino-2-chlorophenyl-5-thiazole; 2-Chloro-4-(1,3-thiazol-5-yl)aniline; 2-Chloro-4-(thiazol-5-yl)benzenamine; 1400287-28-6; 5-(4-Amino-2-chlorophenyl)thiazole; Benzenamine, 2-chloro-4-(5-thiazolyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(Thiazol-5-Yl)Aniline undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and process chemistry. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing lot-specific results are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.