Description

Tetrahydro-4-Oxo-2H-Pyran-3-Sulfonamide is a high-purity, specialized sulfonamide derivative featuring a tetrahydro-4-oxo-2H-pyran scaffold. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce novel sulfonamide-based pharmacophores into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting enzymes or receptors where the sulfonamide group is essential for binding.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry for constructing diverse compound libraries to explore new structure-activity relationships (SAR).
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or plant growth regulators that incorporate heterocyclic sulfonamide structures.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Fine Chemical Synthesis: Acts as a specialized reagent for introducing the tetrahydro-4-oxo-2H-pyran-3-sulfonamide moiety into complex organic molecules.

Basic Information

Product Name	Tetrahydro-4-Oxo-2H-Pyran-3-Sulfonamide
CAS No.	1398606-42-2
Molecular Formula	C5H9NO4S
Molecular Weight	179.19 g/mol
Synonyms	3-Sulfamoyltetrahydro-4H-pyran-4-one; Tetrahydro-4-oxo-2H-pyran-3-sulfonamide; 4-Oxotetrahydro-2H-pyran-3-sulfonamide; 3-Sulfonamidotetrahydro-4H-pyran-4-one; Dihydro-4-oxo-2H-pyran-3-sulfonamide (tautomer); THP-Sulfonamide; 4-Oxo-tetrahydro-pyran-3-sulfonic acid amide
EINECS	Contact for details

Quality Control

Our Tetrahydro-4-Oxo-2H-Pyran-3-Sulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.