Description

(2S,5R)-5-Aminotetrahydro-2H-Pyran-2-Carboxamide Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its defined stereochemistry makes it a critical precursor for the synthesis of complex active pharmaceutical ingredients (APIs) and novel therapeutic agents. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new drugs, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of novel APIs and investigational new drugs.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing complex molecules with specific stereocenters.
• Protease Inhibitor Research: Serves as a core structural component in the development of protease inhibitors for various therapeutic targets.
• Chemical Biology & Drug Discovery: Employed in high-throughput screening and the creation of targeted compound libraries for identifying new biological activities.
• Process Chemistry & Scale-Up: Used in route development and optimization for the efficient, large-scale production of candidate drugs.

Basic Information

Product Name	(2S,5R)-5-Aminotetrahydro-2H-Pyran-2-Carboxamide Hydrochloride
CAS No.	1398571-73-7
Molecular Formula	C7H15ClN2O2
Molecular Weight	194.66 g/mol
Synonyms	(2S,5R)-5-Aminooxane-2-carboxamide hydrochloride; (2S,5R)-5-Aminotetrahydro-2H-pyran-2-carboxamide HCl; 5-Aminotetrahydro-2H-pyran-2-carboxamide hydrochloride, (2S,5R)-; Tetrahydro-2H-pyran-2-carboxamide, 5-amino-, hydrochloride, (2S,5R)-; (2S,5R)-5-Amino-tetrahydropyran-2-carboxylic acid amide hydrochloride
EINECS	Contact for details

Quality Control

Our (2S,5R)-5-Aminotetrahydro-2H-Pyran-2-Carboxamide Hydrochloride is manufactured under strict quality systems suitable for pharmaceutical R&D and production. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.