Description

((2S,5R)-5-Aminotetrahydro-2H-Pyran-2-Yl)Methanol is a high-purity, chiral aminopyran derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a stereochemically defined scaffold essential for constructing complex molecules with high biological specificity. It is primarily needed by research and development teams in the pharmaceutical industry for applications in medicinal chemistry and as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce specific stereochemistry and functional groups.
• Peptidomimetics & Bioisosteres: Serves as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability in drug design.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Agrochemical Research: Potential intermediate in the development of novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.

Basic Information

Product Name	((2S,5R)-5-Aminotetrahydro-2H-Pyran-2-Yl)Methanol
CAS No.	1398569-79-3
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(2S,5R)-5-Aminooxan-2-ylmethanol; (2S,5R)-5-Aminotetrahydro-2H-pyran-2-methanol; (2S,5R)-5-Amino-2-(hydroxymethyl)tetrahydro-2H-pyran; (2S,5R)-2-(Hydroxymethyl)-5-aminotetrahydropyran; (2S,5R)-5-Aminotetrahydro-2-pyranmethanol; (2S,5R)-5-Amino-2-(hydroxymethyl)oxane; (2S,5R)-5-Aminotetrahydro-2H-pyran-2-ylmethanol
EINECS	Contact for details

Quality Control

Our ((2S,5R)-5-Aminotetrahydro-2H-Pyran-2-Yl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.