Description

cis-Ethyl 3-Amino-Tetrahydro-2H-Pyran-4-Carboxylate 2,2,2-Trifluoroacetate is a high-purity, protected amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptidomimetic Synthesis: Used to introduce constrained, heterocyclic amino acid motifs into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Research: Serves as a building block for creating novel, biologically active molecules in crop protection and pesticide development.
• Catalyst and Ligand Preparation: Employed in the synthesis of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Product Name	cis-Ethyl 3-Amino-Tetrahydro-2H-Pyran-4-Carboxylate 2,2,2-Trifluoroacetate
CAS No.	1398504-24-9
Molecular Formula	C10H16F3NO5
Molecular Weight	287.24 g/mol
Synonyms	Ethyl cis-3-Aminooxane-4-carboxylate Trifluoroacetate; Ethyl 3-Amino-tetrahydro-2H-pyran-4-carboxylate TFA Salt; cis-3-Amino-tetrahydro-2H-pyran-4-carboxylic Acid Ethyl Ester 2,2,2-Trifluoroacetate; 4-Carbethoxy-3-amino-tetrahydropyran Trifluoroacetate; (3R,4S)- and (3S,4R)-Ethyl 3-Amino-3,4,5,6-tetrahydro-2H-pyran-4-carboxylate TFA Salt; cis-3-Amino-4-ethoxycarbonyl-tetrahydropyran TFA Salt; 3-Amino-tetrahydro-2H-pyran-4-carboxylic Acid Ethyl Ester, Trifluoroacetic Acid Salt
EINECS	Contact for details

Quality Control

Our cis-Ethyl 3-Amino-Tetrahydro-2H-Pyran-4-Carboxylate 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.