Description

tert-Butyl 3-Oxo-5,7-Dihydro-2H-Pyrrolo[3,4-C]Pyridazine-6(3H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key synthetic building block for constructing complex heterocyclic scaffolds with potential biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing fused pyrrolopyridazine libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Research: Employed in the development of potential kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic structure.
• CNS-Active Compound Synthesis: Serves as a building block for molecules targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in universities and institutes for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 3-Oxo-5,7-Dihydro-2H-Pyrrolo[3,4-C]Pyridazine-6(3H)-Carboxylate
CAS No.	1395493-25-0
Molecular Formula	C11H15N3O3
Molecular Weight	237.26 g/mol
Synonyms	6-(tert-Butoxycarbonyl)-5,7-dihydro-2H-pyrrolo[3,4-c]pyridazin-3(6H)-one; tert-Butyl 3-oxo-2,3,5,7-tetrahydro-6H-pyrrolo[3,4-c]pyridazine-6-carboxylate; 6-Boc-5,7-dihydro-2H-pyrrolo[3,4-c]pyridazin-3(6H)-one; 1395493-25-0; BOC-Pyrrolopyridazinone; tert-Butyl 3-oxo-3,6-dihydro-2H-pyrrolo[3,4-c]pyridazine-6(5H,7H)-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Oxo-5,7-Dihydro-2H-Pyrrolo[3,4-C]Pyridazine-6(3H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.