Description

tert-Butyl 3-Oxo-2,3,5,6-tetrahydropyrido[3,4-c]pyridazine-7(8H)-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its bicyclic heterocyclic structure. This compound is of significant value in medicinal chemistry as a key building block for the synthesis of novel drug candidates, particularly those targeting complex biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of novel compounds in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Its structural motifs are valuable in the design and synthesis of potential protease inhibitors, a major class of therapeutic agents.
• Kinase Inhibitor Synthesis: Employed in the construction of heterocyclic cores found in kinase inhibitor candidates for oncology and inflammatory diseases.
• Chemical Biology Probes: Acts as a starting material for creating specialized molecular probes used to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects requiring high-fidelity, complex intermediates.

Basic Information

Product Name	tert-Butyl 3-Oxo-2,3,5,6-tetrahydropyrido[3,4-c]pyridazine-7(8H)-carboxylate
CAS No.	1395492-99-5
Molecular Formula	C₁₄H₂₁N₃O₃
Molecular Weight	279.34 g/mol
Synonyms	7-(tert-Butoxycarbonyl)-2,3,5,6,7,8-hexahydropyrido[3,4-c]pyridazin-3-one; tert-Butyl hexahydropyrido[3,4-c]pyridazine-7(8H)-carboxylate-3-one; 1395492-99-5; BOC-protected tetrahydropyridopyridazinone; 3-Oxo-2,3,5,6-tetrahydropyrido[3,4-c]pyridazine-7(8H)-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Oxo-2,3,5,6-tetrahydropyrido[3,4-c]pyridazine-7(8H)-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.