Description

(R)-1-Phenylethanamine (S)-2-(6-Hydroxy-2,3-Dihydrobenzofuran-3-Yl)Acetate CAS NO 1394138-46-5 is a high-purity chiral compound that serves as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry, which is essential for creating molecules with specific biological activity and high enantiomeric purity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and cardiovascular therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and cardiovascular targets.
• Asymmetric Synthesis: Used as a resolving agent or chiral auxiliary in stereoselective reactions to produce enantiomerically pure compounds.
• API Development: Serves as a core structural motif in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed in academic and industrial research to study receptor-ligand interactions and enzyme inhibition.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals where precise stereochemistry is required for functionality.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-1-Phenylethanamine (S)-2-(6-Hydroxy-2,3-Dihydrobenzofuran-3-Yl)Acetate
CAS No.	1394138-46-5
Molecular Formula	C18H21NO3
Molecular Weight	299.37 g/mol
Synonyms	(R)-1-Phenylethylammonium (S)-2-(6-Hydroxy-2,3-dihydrobenzofuran-3-yl)acetate; (R)-α-Methylbenzylamine (S)-2-(6-Hydroxy-2,3-dihydrobenzofuran-3-yl)acetate; (R)-1-Phenylethylamine (S)-2-(6-Hydroxy-2,3-dihydrobenzofuran-3-yl)acetate; (R)-PEA (S)-DHBA salt; 1394138-46-5; (R)-1-Phenylethanaminium (S)-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate
EINECS	Contact for details

Quality Control

Our (R)-1-Phenylethanamine (S)-2-(6-Hydroxy-2,3-Dihydrobenzofuran-3-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by spectroscopic methods, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.