Description

Lithium (4-(Trifluoromethyl)Pyridin-2-Yl)Trihydroxyborate is a high-purity organoboron reagent, specifically a lithium trifluoroborate salt, designed for advanced synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, offering superior stability and handling compared to traditional boronic acids. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for constructing complex molecules containing the valuable 4-(trifluoromethyl)pyridyl moiety.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-couplings for synthesizing active pharmaceutical ingredients (APIs) containing trifluoromethylpyridine scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands, and metal-organic frameworks (MOFs).
• Chemical Development: Enables efficient, scalable routes to complex biaryl and heterobiaryl structures in process chemistry and scale-up laboratories.
• Life Science Reagents: Utilized in the synthesis of molecular probes, imaging agents, and diagnostic compounds for research and development.

Basic Information

Item	Details
Product Name	Lithium (4-(Trifluoromethyl)Pyridin-2-Yl)Trihydroxyborate
CAS No.	1393822-85-9
Molecular Formula	C6H6BF3LiNO3
Molecular Weight	200.88 g/mol
Synonyms	Lithium (4-(Trifluoromethyl)pyridin-2-yl)trifluoroborate; 2-(4-Trifluoromethylpyridyl)lithium trifluoroborate; Potassium (4-(Trifluoromethyl)pyridin-2-yl)trifluoroborate (common analogue); 4-(Trifluoromethyl)-2-pyridyltrifluoroborate lithium salt; 2-Pyridyltrifluoroborate lithium salt derivative; (4-Trifluoromethyl-2-pyridyl)trifluoroboronic acid lithium complex; Lithium trifluoro(4-(trifluoromethyl)pyridin-2-yl)borate(1-)
EINECS	Contact for details

Quality Control

Our Lithium (4-(Trifluoromethyl)Pyridin-2-Yl)Trihydroxyborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Keep the container sealed and allow it to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.