Description

3-(3-Chlorophenyl)Oxetane-3-Carboxylic Acid is a high-purity, synthetically valuable oxetane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique oxetane ring fused with a carboxylic acid functionality makes it a versatile intermediate for constructing complex molecular architectures with enhanced physicochemical properties. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, where the oxetane moiety can improve metabolic stability and bioavailability.
• Material Science: Serves as a monomer or cross-linking agent for producing specialized polymers with tailored thermal, mechanical, or optical properties.
• Ligand & Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways due to its ability to mimic transition states or serve as a stable bioisostere.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	3-(3-Chlorophenyl)Oxetane-3-Carboxylic Acid
CAS No.	1393531-96-8
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	3-(3-Chlorophenyl)-3-oxetanecarboxylic acid; 3-Oxetanecarboxylic acid, 3-(3-chlorophenyl)-; 3-(3-Chlorophenyl)oxetane-3-carboxylic acid; 3-(3-Chlorophenyl)oxetane-3-carboxylate; 3-(m-Chlorophenyl)-3-oxetanecarboxylic acid; 3-(3-Chlorophenyl)oxetane-3-carboxylic acid (CAS 1393531-96-8); 3-(3-Chlorophenyl)-3-oxetane carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Chlorophenyl)Oxetane-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation (by NMR and IR), and impurity profile. Our quality commitment supports compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.