Description

(1-Fluorocyclopropyl)Methyl Methanesulfonate is a high-value organofluorine building block and methanesulfonate ester. This compound is critical for introducing the (1-fluorocyclopropyl)methyl moiety into target molecules, a structural motif of significant interest in medicinal chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its specific reactivity profile makes it an essential reagent for advanced organic synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that incorporate fluorinated cyclopropyl groups for enhanced activity and stability.
• Fluorination Reagent: Serves as a source of the (1-fluorocyclopropyl)methyl group in nucleophilic substitution and cross-coupling reactions.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to modulate the physicochemical properties of bioactive molecules.
• Process Chemistry: Used in scale-up and route development for the efficient manufacturing of fluorinated target compounds.
• Chemical Biology Probes: Potential use in the synthesis of labeled compounds or probes for studying biological mechanisms.

Basic Information

Product Name	(1-Fluorocyclopropyl)Methyl Methanesulfonate
CAS No.	1393469-88-9
Molecular Formula	C6H11FO3S
Molecular Weight	182.21 g/mol
Synonyms	(1-Fluorocyclopropyl)methyl methanesulfonate; Methanesulfonic acid (1-fluorocyclopropyl)methyl ester; [(1-Fluorocyclopropyl)methyl] methanesulfonate; 1-Fluorocyclopropylmethyl methanesulfonate; (1-Fluorocyclopropyl)methyl mesylate
EINECS	Contact for details

Quality Control

Our (1-Fluorocyclopropyl)Methyl Methanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.