Description

1-Bromo-2-Chloro-5-(2-Methoxyethoxy)-4-Nitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block for complex organic synthesis. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that require specific halogen and nitro group reactivity.
• Material Science Research: Used in the development of organic electronic materials, liquid crystals, and advanced polymers where its substituents influence electronic properties.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex azo dyes and other colored compounds.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) due to the presence of bromo and chloro leaving groups.
• Organic Synthesis Building Block: Enables nucleophilic aromatic substitution (SNAr) and other transformations for introducing methoxyethoxy and nitro functionalities into target molecules.

Basic Information

Item	Detail
Product Name	1-Bromo-2-Chloro-5-(2-Methoxyethoxy)-4-Nitrobenzene
CAS No.	1393441-69-4
Molecular Formula	C9H9BrClNO4
Molecular Weight	310.53 g/mol
Synonyms	2-Bromo-1-Chloro-4-(2-Methoxyethoxy)-5-Nitrobenzene; 4-Bromo-5-Chloro-2-(2-Methoxyethoxy)-1-Nitrobenzene; 1-Bromo-2-chloro-5-(2-methoxyethoxy)-4-nitro-benzene; Benzene, 1-bromo-2-chloro-5-(2-methoxyethoxy)-4-nitro-; 5-(2-Methoxyethoxy)-2-bromo-1-chloro-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-5-(2-Methoxyethoxy)-4-Nitrobenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.