Description

(3,3-Dimethoxy-Cyclobutyl)Methylamine CAS NO 1392803-86-9 is a versatile and high-value cyclobutane-based amine building block, characterized by its unique 1,3-dioxygenated cyclobutane core. This compound is essential for medicinal chemistry and advanced material synthesis, offering a rigid, functionalized scaffold for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical development, and specialty polymer research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where its structural motif can enhance biological activity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into specialty polymers and dendrimers to modify thermal and mechanical properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and bio-conjugation reagents.
• Peptidomimetics: The constrained cyclobutane ring is valuable for designing peptide analogs with improved metabolic stability.

Basic Information

Product Name	(3,3-Dimethoxy-Cyclobutyl)Methylamine
CAS No.	1392803-86-9
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	1-(Aminomethyl)-3,3-dimethoxycyclobutane; (3,3-Dimethoxycyclobutyl)methanamine; 3,3-Dimethoxycyclobutanemethylamine; N-(3,3-Dimethoxycyclobutyl)methylamine; Cyclobutanemethanamine, 3,3-dimethoxy-; (3,3-Dimethoxy-cyclobutyl)-methylamine; Aminomethyl-3,3-dimethoxycyclobutane
EINECS	Contact for details

Quality Control

Every batch of (3,3-Dimethoxy-Cyclobutyl)Methylamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.