Description

(3S)-5-Oxo-3-Morpholinecarboxylic Acid 1,1-Dimethylethyl Ester is a high-purity, chiral morpholine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected carboxylic acid and a versatile nitrogen-oxygen heterocycle, enabling the efficient construction of complex pharmaceutical intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Acts as a constrained amino acid analog in the design of peptide-like molecules with enhanced metabolic stability.
• Catalyst Ligand Precursor: Can be utilized to develop novel chiral ligands for asymmetric catalysis.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke client projects requiring specialized morpholine chemistry.

Basic Information

Product Name	(3S)-5-Oxo-3-Morpholinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	1391062-29-5
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	tert-Butyl (3S)-5-oxomorpholine-3-carboxylate; (S)-tert-Butyl 5-oxomorpholine-3-carboxylate; (3S)-5-Oxo-3-morpholinecarboxylic acid tert-butyl ester; (S)-tert-Butyl 2-oxo-1,4-oxazinane-4-carboxylate; (S)-1,4-Oxazinane-2-one, 4-(tert-butoxycarbonyl)-; BOC-Morpholinone; Chiral Morpholinone Ester
EINECS	Contact for details

Quality Control

Our (3S)-5-Oxo-3-Morpholinecarboxylic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee supply chain transparency and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.