Description

3-(Boc-Amino)-2-Amino-1-Propanol is a bifunctional amino alcohol derivative featuring both a primary amine and a tert-butoxycarbonyl (Boc)-protected secondary amine group. This compound serves as a versatile and crucial chiral building block in advanced organic synthesis, enabling the controlled introduction of amino alcohol motifs. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other biologically active molecules.
• Peptidomimetics & Conjugate Chemistry: Used in the preparation of peptide analogs and antibody-drug conjugates (ADCs) due to its orthogonal amine protection.
• Ligand & Catalyst Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complexation.
• Polymer & Material Science: Employed as a monomer or cross-linking agent for producing functionalized polymers with amine groups.
• Agrochemical Research: Acts as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in diagnostic and research applications.

Basic Information

Product Name	3-(Boc-Amino)-2-Amino-1-Propanol
CAS No.	1391046-15-3
Molecular Formula	C8H18N2O3
Molecular Weight	190.24 g/mol
Synonyms	1-Amino-3-[(tert-butoxycarbonyl)amino]-2-propanol; 2-Amino-3-(Boc-amino)-1-propanol; 3-[(tert-Butoxycarbonyl)amino]-2-amino-1-propanol; (2-Amino-3-hydroxypropyl)carbamic acid tert-butyl ester; Boc-Dap-ol; N-Boc-1,3-diamino-2-propanol; tert-Butyl N-(2-amino-3-hydroxypropyl)carbamate; 1,3-Diamino-2-propanol, N-Boc derivative
EINECS	Contact for details

Quality Control

Our 3-(Boc-Amino)-2-Amino-1-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.