Description

1-Ethoxymethyl-Cyclobutanecarboxylic Acid is a specialized cyclobutane derivative carboxylic acid ester, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and an ethoxymethyl ether group, makes it a versatile building block for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring constrained, rigid cyclobutane ring systems.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclobutane core can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for constructing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-Ethoxymethyl-Cyclobutanecarboxylic Acid
CAS No.	1387557-17-6
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	Cyclobutanecarboxylic acid, 1-(ethoxymethyl)-; 1-(Ethoxymethyl)cyclobutanecarboxylic acid; 1-Ethoxymethylcyclobutan-1-carboxylic acid; (1-(Ethoxymethyl)cyclobutyl)formic acid
EINECS	Contact for details

Quality Control

Our 1-Ethoxymethyl-Cyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.