Description

1-(3-Fluoro-4-Methoxyphenyl)-4-Oxocyclohexanecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated and methoxy-substituted aromatic ring system. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for synthesizing more complex fluorinated and methoxy-containing heterocyclic compounds.
• Contract Manufacturing: Employed in cGMP production for clinical trial materials and commercial-scale API manufacturing.
• Agrochemical Research: Potential intermediate in the development of novel fluorinated agrochemicals and pesticides.
• Material Science: Exploration of applications in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(3-Fluoro-4-Methoxyphenyl)-4-Oxocyclohexanecarboxylic Acid
CAS No.	1385694-60-9
Molecular Formula	C14H15FO4
Molecular Weight	266.26 g/mol
Synonyms	4-Oxo-1-[3-fluoro-4-methoxyphenyl]cyclohexanecarboxylic Acid; 1-(3-Fluoro-4-methoxyphenyl)-4-oxocyclohexane-1-carboxylic Acid; 4-Oxo-1-(3-fluoro-4-methoxyphenyl)cyclohexanecarboxylic Acid; Cyclohexanecarboxylic acid, 1-(3-fluoro-4-methoxyphenyl)-4-oxo-; 1385694-60-9; 1-(3-Fluoro-4-methoxyphenyl)-4-oxocyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our production of 1-(3-Fluoro-4-Methoxyphenyl)-4-Oxocyclohexanecarboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.