Description

cis-3-Hydroxy-3-Methylcyclobutanecarboxylic Acid is a specialized chiral building block featuring a unique cyclobutane ring system. This compound is valued for its structural rigidity and the presence of both carboxylic acid and hydroxyl functional groups, which make it a versatile intermediate for advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclobutane core can impart specific biological activity and stability.
• Advanced Material Research: Serves as a monomer or precursor for developing specialty polymers with tailored thermal or mechanical properties.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in ring-strain chemistry and stereochemistry.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value chemicals for various industrial and research applications.

Basic Information

Product Name	cis-3-Hydroxy-3-Methylcyclobutanecarboxylic Acid
CAS No.	1384855-41-7
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(1r,3s)-3-Hydroxy-3-methylcyclobutanecarboxylic acid; (1R,3S)-3-Hydroxy-3-methylcyclobutanecarboxylic acid; cis-3-Hydroxy-3-methyl-1-cyclobutanecarboxylic Acid; 3-Methyl-3-hydroxycyclobutanecarboxylic acid; 3-Hydroxy-3-methylcyclobutanecarboxylic acid, cis-; (1R,3S)-3-Hydroxy-3-methyl-1-cyclobutanecarboxylic acid; 1384855-41-7; cis-3-Hydroxy-3-methylcyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our cis-3-Hydroxy-3-Methylcyclobutanecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality, identity, and purity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.