Description

n-(3-Bromophenyl)Pyrrolidin-3-Amine is a high-purity brominated pyrrolidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine-substituted aromatic and pyrrolidine amine functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional polymers where its molecular structure imparts specific electronic or physical properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways due to its amine handle for further conjugation.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring precise bromine substitution on an aniline-pyrrolidine hybrid structure.

Basic Information

Product Name	n-(3-Bromophenyl)Pyrrolidin-3-Amine
CAS No.	1379367-65-3
Molecular Formula	C10H13BrN2
Molecular Weight	241.13 g/mol
Synonyms	3-((3-Bromophenyl)amino)pyrrolidine; 1-(3-Bromophenyl)-3-aminopyrrolidine; N-(3-Bromophenyl)-3-pyrrolidinamine; 3-Amino-N-(3-bromophenyl)pyrrolidine; 3-Pyrrolidinamine, N-(3-bromophenyl)-; (3-Bromophenyl)(3-pyrrolidinyl)amine
EINECS	Contact for details

Quality Control

Every batch of n-(3-Bromophenyl)Pyrrolidin-3-Amine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are supplied with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.