Description

Cyclobutanecarboxylic Acid, 3-Bromo- CAS NO 1378752-12-5 is a high-purity, functionalized cyclobutane derivative serving as a versatile and critical building block in advanced organic synthesis. Its unique strained-ring structure, combined with the reactive bromine and carboxylic acid functional groups, makes it an invaluable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand design, and polymer research.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the cyclobutane ring can impart favorable biological activity and environmental profile.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis, leveraging the steric and electronic properties of the substituted cyclobutane ring.
• Chemical Biology Probe: Utilized as a scaffold or labeling reagent in the design of molecular probes for studying enzyme function and protein-protein interactions.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Bromo-
CAS No.	1378752-12-5
Molecular Formula	C5H7BrO2
Molecular Weight	179.01 g/mol
Synonyms	3-Bromocyclobutanecarboxylic Acid; 3-Bromocyclobutane-1-carboxylic Acid; (3-Bromocyclobutyl)carboxylic Acid; 1-Carboxy-3-bromocyclobutane; Cyclobutane-1-carboxylic acid, 3-bromo-; 3-Bromo-1-cyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromocyclobutanecarboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.