Description

Imidazo[1,2-B]Pyridazin-8(5H)-One CAS NO 1376761-89-5 is a high-purity heterocyclic organic compound belonging to the fused pyridazine class. This advanced pharmaceutical intermediate is critical for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable building blocks for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Kinase Inhibitor Development: Serves as a core scaffold for designing potent and selective kinase inhibitors for cancer therapy.
• CNS Drug Discovery: Employed in the research of compounds for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke molecules for client projects.

Basic Information

Product Name	Imidazo[1,2-B]Pyridazin-8(5H)-One
CAS No.	1376761-89-5
Molecular Formula	C6H5N3O
Molecular Weight	135.12 g/mol
Synonyms	8H-Imidazo[1,2-b]pyridazin-8-one; Imidazo[1,2-b]pyridazin-8(5H)-one; 5H-Imidazo[1,2-b]pyridazin-8-one; Imidazo[1,2-b]pyridazin-8-ol; 8-Oxo-5,8-dihydroimidazo[1,2-b]pyridazine
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-B]Pyridazin-8(5H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.