Description

Potassium (5-Chloropyridin-2-yl)trifluoroborate is an organotrifluoroborate salt, a highly valuable and stable synthetic intermediate in modern organic chemistry. Its primary value lies in its exceptional utility in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing chloropyridine motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific chlorinated heterocyclic architectures.
• Material Science: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
• Cross-Coupling Reactions: Specifically designed for robust and predictable palladium-catalyzed Suzuki-Miyaura couplings with various aryl and heteroaryl halides.
• Chemical Research: An indispensable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel compound libraries.
• Ligand and Catalyst Development: Used to synthesize complex ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	Potassium (5-Chloropyridin-2-yl)trifluoroborate
CAS No.	1375328-10-1
Molecular Formula	C5H3BClF3KN
Molecular Weight	213.44 g/mol
Synonyms	Potassium 5-Chloropyridin-2-yltrifluoroborate; 5-Chloro-2-pyridyltrifluoroborate Potassium Salt; (5-Chloro-2-pyridinyl)trifluoroboronic Acid Potassium Salt; Potassium (5-Chloro-2-pyridyl)trifluoroborate; 2-(5-Chloropyridinyl)trifluoroborate Potassium; Potassium Trifluoro(5-chloropyridin-2-yl)borate; 5-Chloropyridine-2-trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium (5-Chloropyridin-2-yl)trifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, critical for sensitive cross-coupling applications. All products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Purity	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.