Description

4-[3-(Carboxymethyl)Phenyl]Benzoic Acid is a high-purity, functionalized biphenyl derivative serving as a critical building block in advanced organic synthesis. Its dual carboxylic acid functionality makes it a versatile intermediate for constructing complex molecular architectures, particularly in the development of specialty polymers and pharmaceuticals. This compound is essential for R&D chemists and process engineers in the fine chemical, pharmaceutical, and advanced materials sectors seeking reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting inflammation or central nervous system disorders.
• Liquid Crystal & OLED Materials: Serves as a core structure for creating novel monomers and polymers used in display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Used to introduce carboxylic acid groups into polymer backbones, enhancing properties like adhesion, solubility, and cross-linking capability.
• Metal-Organic Framework (MOF) Synthesis: Acts as an organic linker or ligand in the construction of porous coordination polymers for catalysis and gas storage.
• Agrochemical Synthesis: Intermediate in the development of new herbicides and plant growth regulators with specific activity profiles.
• Dye & Pigment Manufacturing: Building block for synthesizing complex organic dyes and pigments with improved stability and color properties.
• Cross-coupling Reactions: Valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl systems.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new synthetic pathways in medicinal and materials chemistry.

Basic Information

Product Name	4-[3-(Carboxymethyl)Phenyl]Benzoic Acid
CAS No.	1375068-94-2
Molecular Formula	C16H14O4
Molecular Weight	270.28 g/mol
Synonyms	3'-(Carboxymethyl)-[1,1'-biphenyl]-4-carboxylic acid; 4'-(Carboxymethyl)biphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 3'-(carboxymethyl)-; 3-Carboxymethyl-4'-carboxybiphenyl; Biphenyl-3,4'-dicarboxylic acid, 3-methyl ester (related); 4-(3-Carboxymethylphenyl)benzoic acid; 4-(3-Methoxycarbonylphenyl)benzoic acid (methyl ester precursor); 3'-Methoxycarbonylbiphenyl-4-carboxylic acid (methyl ester form)
EINECS	Contact for details

Quality Control

Our 4-[3-(Carboxymethyl)Phenyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.