Description

3-(Boc-Amino)-3-Methylcyclohexanone is a high-purity, protected amino ketone building block essential for advanced organic synthesis. This compound is valued for its role in introducing the tert-butoxycarbonyl (Boc) protected amine functionality into complex molecular frameworks, a critical step in peptide mimetics and pharmaceutical intermediate development. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic diseases.
• Peptidomimetic Chemistry: Serves as a crucial building block for creating non-peptide scaffolds that mimic the structure and function of peptides, enhancing metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators requiring complex cyclohexanone-based structures.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP or research-grade conditions.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, including studies on asymmetric catalysis and ring-forming reactions.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.

Basic Information

Product Name	3-(Boc-Amino)-3-Methylcyclohexanone
CAS No.	1374657-01-8
Molecular Formula	C₁₂H₂₁NO₃
Molecular Weight	227.30 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-3-methylcyclohexanone; 3-(Boc-amino)-3-methylcyclohexan-1-one; tert-Butyl (3-methyl-3-oxocyclohexyl)carbamate; 3-Methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexan-1-one; Boc-3-amino-3-methylcyclohexanone; N-Boc-3-amino-3-methylcyclohexanone
EINECS	Contact for details

Quality Control

Every batch of 3-(Boc-Amino)-3-Methylcyclohexanone is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) for each lot, which includes data from NMR, HPLC, and mass spectrometry. Our quality commitment aligns with the standards expected for research and development use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.