Description

6-Chloro-2,3-Difluorobenzylamine, 97% is a high-purity, multi-functional aromatic amine building block featuring a benzylamine core with strategically positioned chlorine and fluorine substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogen pattern enables precise modulation of biological activity and physicochemical properties. It is a critical intermediate for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic effects into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro and chloro groups enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Monomer: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in exploring new chemical spaces and structure-activity relationships (SAR).
• Fluorinated Compound Library: Integral for constructing diverse libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	6-Chloro-2,3-Difluorobenzylamine, 97%
CAS No.	1373921-11-9
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	(6-Chloro-2,3-difluorophenyl)methanamine; 1-(6-Chloro-2,3-difluorophenyl)methanamine; 2,3-Difluoro-6-chlorobenzylamine; 6-Chloro-2,3-difluorobenzylamine; 6-Chloro-2,3-difluorobenzenemethanamine; Benzenemethanamine, 6-chloro-2,3-difluoro-; (6-Chloro-2,3-difluorobenzyl)amine
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,3-Difluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the specified 97% minimum purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The compound is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.