Description

tert-Butyl 2-Amino-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate is a high-value heterocyclic building block with a fused thienopyran core. This compound matters as a critical synthetic intermediate, enabling the construction of complex molecular architectures for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a specialized monomer or precursor for advanced organic electronic materials and functional polymers.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for synthetic methodology development and exploration of new chemical space in university and CRO laboratories.
• Custom Synthesis & Scale-Up: A starting point for contract manufacturing organizations (CMOs) to produce customized advanced intermediates for client projects.

Basic Information

Product Name	tert-Butyl 2-Amino-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate
CAS No.	1373496-97-9
Molecular Formula	C14H21NO3S
Molecular Weight	283.39 g/mol
Synonyms	2-Amino-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester; tert-Butyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate; 4H-Thieno[2,3-c]pyran-3-carboxylic acid, 2-amino-5,5-dimethyl-5,7-dihydro-, 1,1-dimethylethyl ester; 1373496-97-9; TBADTPC; ATB Thienopyran Ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-Amino-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for all shipments, supporting compliance in GMP-aligned research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.