Description

6-[Bis[(1,1-Dimethylethoxy)Carbonyl]Amino]-5-[(1R)-1- (2,6-Dichloro-3-Fluorophenyl)Ethoxy]-3-Pyridazinecarboxylic Acid Ethyl Ester CAS NO 1370651-34-5 is a high-purity, advanced pharmaceutical intermediate characterized by its complex pyridazinecarboxylic acid ester structure. This compound is of critical importance for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Drug Discovery & Development: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry: Employed in route scouting and scale-up activities for the production of candidate drug molecules in preclinical and clinical development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global biopharma industry.
• Academic Research: Utilized in university and institutional labs for biochemical research and the study of enzyme inhibitors or receptor modulators.

Basic Information

Product Name	6-[Bis[(1,1-Dimethylethoxy)Carbonyl]Amino]-5-[(1R)-1- (2,6-Dichloro-3-Fluorophenyl)Ethoxy]-3-Pyridazinecarboxylic Acid Ethyl Ester
CAS No.	1370651-34-5
Molecular Formula	C25H30Cl2FN3O7
Molecular Weight	590.43 g/mol
Synonyms	Ethyl 6-((bis(tert-butoxycarbonyl)amino)-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridazine-3-carboxylate; 6-[Bis(tert-Butoxycarbonyl)Amino]-5-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)Ethoxy]pyridazine-3-carboxylic Acid Ethyl Ester; 1370651-34-5; UNII-9Q5V1U2K6F; 9Q5V1U2K6F; SCHEMBL23301195; AKOS040757623; DB14951
EINECS	Contact for details

Quality Control

Our 6-[Bis[(1,1-Dimethylethoxy)Carbonyl]Amino]-5-[(1R)-1- (2,6-Dichloro-3-Fluorophenyl)Ethoxy]-3-Pyridazinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Single Maximum Impurity	≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.