Description

4-tert-Butyl-3-(Cyclopropylmethoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique substituted aniline structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its aniline core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel ligands used in catalytic processes.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	4-tert-Butyl-3-(Cyclopropylmethoxy)Aniline
CAS No.	1369783-74-3
Molecular Formula	C14H21NO
Molecular Weight	219.32 g/mol
Synonyms	3-(Cyclopropylmethoxy)-4-(tert-butyl)aniline; 4-(tert-Butyl)-3-(cyclopropylmethoxy)benzenamine; 4-tert-Butyl-3-(cyclopropylmethoxy)phenylamine; Benzenamine, 4-(1,1-dimethylethyl)-3-(cyclopropylmethoxy)-; 4-tert-Butyl-3-cyclopropylmethoxyaniline
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-3-(Cyclopropylmethoxy)Aniline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.