Description

2-(3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazin-7-Yl)Acetic Acid is a high-purity pharmaceutical intermediate and organic building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. This compound is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to innovate and scale new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex benzoxazine derivatives and exploring new chemical spaces in medicinal chemistry.
• Agrochemical Development: Serves as a precursor for creating new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Potential monomer or additive for developing specialty polymers, coatings, or advanced organic electronic materials.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis and scale-up projects under cGMP conditions.
• Process Chemistry: Utilized in route scouting and optimization for the commercial-scale production of target molecules.

Basic Information

Item	Details
Product Name	2-(3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazin-7-Yl)Acetic Acid
CAS No.	1368148-71-3
Molecular Formula	C12H11NO4
Molecular Weight	233.22 g/mol
Synonyms	7-Carboxymethyl-2H-1,4-benzoxazin-3(4H)-one; 2-(3-Oxo-4H-1,4-benzoxazin-7-yl)acetic acid; 7-(Carboxymethyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one; 2-(3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)ethanoic acid; Benzo[b][1,4]oxazin-7-acetic acid, 3,4-dihydro-3-oxo-; 1368148-71-3
EINECS	Contact for details

Quality Control

Our 2-(3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazin-7-Yl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request, ensuring traceability and regulatory compliance for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.