Description

(1R,4R)-N1-(4-Chlorobenzyl)Cyclohexane-1,4-Diamine Hydrochloride is a high-purity chiral diamine hydrochloride salt, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a sophisticated intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its defined stereochemistry is essential for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides with specific stereochemical requirements for efficacy.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for complex, high-value chemical entities.
• Academic & R&D: Serves as a standard or starting material in university and industrial research laboratories exploring new synthetic methodologies.

Basic Information

Product Name	(1R,4R)-N1-(4-Chlorobenzyl)Cyclohexane-1,4-Diamine Hydrochloride
CAS No.	1366386-68-6
Molecular Formula	C14H22Cl2N2
Molecular Weight	289.24 g/mol
Synonyms	(1R,4R)-N-[(4-Chlorophenyl)methyl]cyclohexane-1,4-diamine hydrochloride; (1R,4R)-N1-(4-Chlorobenzyl)-1,4-diaminocyclohexane hydrochloride; (1R,4R)-4-[(4-Chlorobenzyl)amino]cyclohexan-1-amine hydrochloride; (1R,4R)-N-(4-Chlorobenzyl)cyclohexane-1,4-diamine HCl; rel-(1R,4R)-N1-[(4-Chlorophenyl)methyl]cyclohexane-1,4-diamine hydrochloride; (1R,4R)-N-(p-Chlorobenzyl)cyclohexane-1,4-diamine hydrochloride; 1,4-Cyclohexanediamine, N1-[(4-chlorophenyl)methyl]-, (1R,4R)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,4R)-N1-(4-Chlorobenzyl)Cyclohexane-1,4-Diamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.