Description

2-(Trimethylsilyl)Ethyl (2-(5-Bromopyrimidin-2-Yl)Propan-2-Yl)Carbamate is a specialized, high-purity synthetic intermediate designed for advanced pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a potential component in the linker or ligand structures for bifunctional degrader molecules.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific compounds at various scales.
• Academic Research: Used in university and institutional laboratories for fundamental research in organic synthesis and new methodology development.

Basic Information

Product Name	2-(Trimethylsilyl)Ethyl (2-(5-Bromopyrimidin-2-Yl)Propan-2-Yl)Carbamate
CAS No.	1364719-02-7
Molecular Formula	C13H22BrN3O2Si
Molecular Weight	360.33 g/mol
Synonyms	2-(Trimethylsilyl)ethyl N-[2-(5-bromopyrimidin-2-yl)propan-2-yl]carbamate; Carbamic acid, N-[2-(5-bromo-2-pyrimidinyl)-1,1-dimethylethyl]-, 2-(trimethylsilyl)ethyl ester; 1364719-02-7; 2-(TMS)ethyl (2-(5-bromopyrimidin-2-yl)propan-2-yl)carbamate; (2-(Trimethylsilyl)ethoxy)carbonyl-protected amine derivative; 5-Bromo-2-(1-(((2-(trimethylsilyl)ethoxy)carbonyl)amino)-1-methylethyl)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-(Trimethylsilyl)Ethyl (2-(5-Bromopyrimidin-2-Yl)Propan-2-Yl)Carbamate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity suitable for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and performance. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.