Description

1H-Pyrazolo[4,3-B]Pyridine-7-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and material science. The consistent quality and reliable supply of this intermediate are paramount for accelerating R&D timelines and ensuring reproducible results.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Development: Serves as a precursor in the creation of new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Precursor: Potential starting material for the synthesis of organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up activities.

Basic Information

Item	Detail
Product Name	1H-Pyrazolo[4,3-B]Pyridine-7-Carboxylic Acid
CAS No.	1363383-15-6
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	7-Pyrazolo[4,3-b]pyridinecarboxylic Acid; 1H-Pyrazolo[4,3-b]pyridine-7-carboxylic acid; Pyrazolo[4,3-b]pyridine-7-carboxylic acid; 7-Carboxy-1H-pyrazolo[4,3-b]pyridine; 1363383-15-6; 1H-Pyrazolo[4,3-b]pyridine-7-carboxylic acid; 7-Pyrazolo[4,3-b]pyridine carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-B]Pyridine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.