Description

3-Methylisoxazol-5-Yl Trifluoromethanesulfonate is a high-purity chemical intermediate designed for advanced synthetic applications. This compound is valued for its role as a versatile triflate ester, enabling efficient functional group transformations and cross-coupling reactions in complex molecule construction. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing the isoxazole heterocycle.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Cross-Coupling Reactions: Serves as an effective electrophile in palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Material Science Research: Employed in the development of advanced organic materials and ligands for catalysis.
• Process Chemistry: Utilized in route scouting and optimization for scalable manufacturing processes.

Basic Information

Product Name	3-Methylisoxazol-5-Yl Trifluoromethanesulfonate
CAS No.	1363210-15-4
Molecular Formula	C6H4F3NO4S
Molecular Weight	243.16 g/mol
Synonyms	5-(Trifluoromethanesulfonyloxy)-3-methylisoxazole; 3-Methyl-5-isoxazolyl Triflate; 3-Methylisoxazol-5-yl Triflate; 3-Methyl-5-(trifluoromethanesulfonyloxy)isoxazole; Trifluoromethanesulfonic Acid 3-Methylisoxazol-5-yl Ester; 3-Methyl-1,2-oxazol-5-yl trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Every batch of 3-Methylisoxazol-5-Yl Trifluoromethanesulfonate is produced under strict quality management protocols. Our products undergo rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.