Description

2-Bromoimidazo[1,2-B]Pyridazine is a high-value brominated heterocyclic building block, primarily utilized in advanced pharmaceutical and agrochemical research and development. Its core value lies in enabling the synthesis of novel, complex molecules by serving as a key intermediate for cross-coupling reactions and functional group transformations. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries who are developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic scaffolds.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form C-C and C-N bonds.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development and exploratory synthesis.

Basic Information

Item	Detail
Product Name	2-Bromoimidazo[1,2-B]Pyridazine
CAS No.	1363166-47-5
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	2-Bromoimidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine, 2-bromo-; 2-Bromo-imidazo[1,2-b]pyridazine; 1363166-47-5; AI3-52335; ZINC000103223536; AKOS040759947; BRN 12506147; 2-Bromoimidazo(1,2-b)pyridazine
EINECS	Contact for details

Quality Control

Our 2-Bromoimidazo[1,2-B]Pyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.