Description

(1Z,3Z)-1,3-Bis[[(4S)-4,5-Dihydro-4-(tert-Butyl)-2-Oxazolyl]Methylene]-2,3-Dihydro-1H-Isoindole is a sophisticated chiral oxazoline-based ligand precursor, valued for its ability to induce high stereoselectivity in catalytic transformations. This compound is essential for researchers and manufacturers developing advanced asymmetric synthesis routes for pharmaceuticals and fine chemicals. Its primary utility lies in the synthesis of highly selective metal-ligand complexes used in organic synthesis and catalysis.

Application

• As a key chiral ligand precursor in asymmetric catalysis for pharmaceutical intermediate synthesis.
• In the development of transition metal complexes for enantioselective hydrogenation and carbon-carbon bond-forming reactions.
• For research and process development in fine chemical and agrochemical manufacturing.
• As a building block for novel organocatalysts and specialty materials.
• In academic and industrial R&D for exploring new stereoselective synthetic methodologies.

Basic Information

Product Name	(1Z,3Z)-1,3-Bis[[(4S)-4,5-Dihydro-4-(tert-Butyl)-2-Oxazolyl]Methylene]-2,3-Dihydro-1H-Isoindole
CAS No.	1361563-41-8
Molecular Formula	C26H32N2O2
Molecular Weight	404.55 g/mol
Synonyms	(1Z,3Z)-1,3-Bis[(4S)-4-(tert-Butyl)-4,5-dihydro-2-oxazolylmethylene]-2,3-dihydro-1H-isoindole; (S,S)-1,3-Bis(4-tert-butyl-2-oxazolinylmethylene)isoindoline; Chiral Bis(oxazoline) Ligand Precursor; BOX Ligand Derivative; (Z,Z)-Isomer of Chiral Dihydroisoindole Bisoxazoline; (4S,4'S)-4,4'-Di-tert-butyl-2,2'-(1Z,3Z)-2,3-dihydro-1H-isoindole-1,3-diylidenebis(methylene)bis(4,5-dihydrooxazole)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and isomeric composition, supporting critical research and process development. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and analytical data (NMR, HPLC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.